Nature's Miracle Enzymatic Formula Urine Destroyer Plus Dog Stain & Odor Remover, 32-fl oz spray bottle. Starts to break down and remove dog urine stains on contact. Easy to use—simply soak the affected area, allow to work for 15 minutes, then blot with a clean cloth.. The enzymatic formula keeps working as long as any bio-based mess is present. Nature’s Miracle bottles are designed with 25% post-consumer recycled material. Safe for use around your pets and home when used and stored as directed.